The fourth Ethiopian HIV/AIDS Prevention Summit, held in Jigjiga, capital of the Somali Regional state of Ethiopia, 29-30 December 2014, drew attention to the concerning rise in HIV prevalence in the region. HIV prevalence has increased to 1,1% in 2014 from 0,7% in 2011. The national HIV/AIDS prevention summit called for intensified HIV response efforts in the region and the entire country.